Size:100ul
$319.00
In Stock
SKU
OADC00013
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More Information
Predicted Species Reactivity Human
Product Format Liquid. Whole antiserum from rabbit containing 0.05% azide.
Clonality Polyclonal
Host Rabbit
Conjugation Unconjugated
Application CHIP
Reconstitution and Storage Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item This antibody may replace item sc-122480 from Santa Cruz Biotechnology.
Purification Whole antiserum
Concentration Undetermined, ascites
Datasheets/Manuals Printable datasheet for anti-CBFB (OADC00013) antibody
Preservative 0.05% Sodium Azide
Specificity Polyclonal antibody raised in rabbit against human CBFb (core-binding factor, beta subunit) using two KLH-conjugated synthetic peptides containing sequences from the central region of the protein.
Application Info CHIP: 4 ul/CHIP
ELISA: 1:500
Gene Symbol CBFB
Official Gene Full Name core-binding factor, beta subunit
Alias Symbols PEBP2B
NCBI Gene Id 865;
Protein Name core-binding factor subunit beta
Description of Target The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Two transcript variants encoding different isoforms have been found for this gene.
Swissprot Id Q13951
Protein Accession # NP_001746.1
Nucleotide Accession # NM_001755.2
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express CBFB.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express CBFB.
  1. What is the species homology for "CBFB Antibody (OADC00013)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "CBFB Antibody (OADC00013)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "CBFB Antibody (OADC00013)" provided in?

    This item is provided in "Liquid. Whole antiserum from rabbit containing 0.05% azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CBFB Antibody (OADC00013)"?

    This target may also be called "PEBP2B" in publications.

  5. What is the shipping cost for "CBFB Antibody (OADC00013)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CBFB Antibody (OADC00013)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CBFB Antibody (OADC00013)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CBFB Antibody (OADC00013)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "CBFB"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CBFB"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CBFB"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CBFB"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CBFB"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CBFB"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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