Size:100 ug
$269.00
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SKU
OABB02007
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More Information
Predicted Species Reactivity Human, Mouse, Rat
Product Format Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application WB, IHC-P
Reconstitution and Storage Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml. +4C
Replacement Item This antibody may replace item sc-101216 from Santa Cruz Biotechnology.
Immunogen E.coli-derived human BAG2 recombinant protein (Position: M1-N211). Human BAG2 shares 93.4% amino acid (aa) sequence identity with mouse BAG2.
Purification Immunogen affinity purified.
Peptide Sequence Synthetic peptide located within the following region: MAQAKINAKANEGRFCRSSSMADRSSRLLESLDQLELRVEALREAATAVEQEKEILLEMIHSIQNSQDMRQISDGEREELNLTANRLMGRTLTVEVSVETIRNPQQQESLKHATRIIDEVVNKFLDDLGNAKSHLMSLYSACSSEVPHGPVDQKFQSIVIGCALEDQKKIKRRLETLLRNIENSDKAIKLLEHSKGAGSKTLQQNAESRFN
Datasheets/Manuals Printable datasheet for anti-BAG2 (OABB02007) antibody
Application Info Tested Species: In-house tested species with positive results.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Target Reference 1. Takayama S, Xie Z, Reed JC (Feb 1999). "An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators". J Biol Chem 274 (2): 781–6.
2. "Entrez Gene: BAG2 BCL2-associated athanogene 2".
Gene Symbol BAG2
Official Gene Full Name BAG family molecular chaperone regulator 2
Alias Symbols BAG-2, dJ417I1.2
NCBI Gene Id 9532
Description of Target BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. The functional antagonisms displayed between BAG family proteins and Hip suggest that a proper balance of these 2 types of protein is required for achieving optimal cycles of substrate binding and release required for inducting conformational changes in proteins, with Hip promoting peptide substrate binding by Hsc70/Hsp70 and BAG family proteins promoting dissociation.
Swissprot Id O95816
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express BAG2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express BAG2.
  1. What is the species homology for "BAG2 Antibody (OABB02007)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "BAG2 Antibody (OABB02007)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "BAG2 Antibody (OABB02007)" provided in?

    This item is provided in "Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "BAG2 Antibody (OABB02007)"?

    This target may also be called "BAG-2, dJ417I1.2" in publications.

  5. What is the shipping cost for "BAG2 Antibody (OABB02007)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "BAG2 Antibody (OABB02007)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "BAG2 Antibody (OABB02007)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "BAG2 Antibody (OABB02007)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "BAG2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "BAG2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "BAG2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "BAG2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "BAG2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "BAG2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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