Size:100 ul
Special Price $229.00 Regular Price $249.00
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ARP42177_T100
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Conjugation Options

ARP42177_T100-FITC Conjugated

ARP42177_T100-HRP Conjugated

ARP42177_T100-Biotin Conjugated

BAG2 Antibody - C-terminal region (ARP42177_T100)

Rating:
100% of 100
Catalog#: ARP42177_T100
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application IHC, WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-101216 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human BAG2
Purification Protein A purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Complete computational species homology data Anti-BAG2 (ARP42177_T100)
Peptide Sequence Synthetic peptide located within the following region: VDQKFQSIVIGCALEDQKKIKRRLETLLRNIENSDKAIKLLEHSKGAGSK
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-BAG2 (ARP42177_T100) antibody is Catalog # AAP42177 (Previous Catalog # AAPP24602)
Datasheets/Manuals Printable datasheet for anti-BAG2 (ARP42177_T100) antibody
Sample Type Confirmation

BAG2 is supported by BioGPS gene expression data to be expressed in Jurkat

Target Reference Arndt,V., (2005) Mol. Biol. Cell 16 (12), 5891-5900
Publications

Yue, X; Zhao, Y; Liu, J; Zhang, C; Yu, H; Wang, J; Zheng, T; Liu, L; Li, J; Feng, Z; Hu, W; BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function. 4, (2015). IHC, WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish 26271008

Gene Symbol BAG2
Official Gene Full Name BCL2-associated athanogene 2
Alias Symbols RP3-496N17.2, BAG-2, KIAA0576, MGC149462, dJ417I1.2
NCBI Gene Id 9532
Protein Name BAG family molecular chaperone regulator 2
Description of Target BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Swissprot Id O95816
Protein Accession # NP_004273
Nucleotide Accession # NM_004282
Protein Size (# AA) 211
Molecular Weight 23kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express BAG2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express BAG2.
Protein Interactions BAG2; UBC; TP53; LGALS3BP; TUBGCP2; TUBG1; STIP1; TAB1; STUB1; DNAJB6; MLF2; TTC1; STXBP2; SGTA; DNAJB1; HSPA8; SHFM1; PINK1; RPA3; RPA2; RPA1; AHNAK; PARK2; LATS2; TARDBP; EGFR; BAG3; HDAC11; SOX2; NPM1; PAN2; WDR83; WDR77; CCAR2; METTL21B; DNAJC6; NOS2;
  1. What is the species homology for "BAG2 Antibody - C-terminal region (ARP42177_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish".

  2. How long will it take to receive "BAG2 Antibody - C-terminal region (ARP42177_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "BAG2 Antibody - C-terminal region (ARP42177_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "BAG2 Antibody - C-terminal region (ARP42177_T100)"?

    This target may also be called "RP3-496N17.2, BAG-2, KIAA0576, MGC149462, dJ417I1.2" in publications.

  5. What is the shipping cost for "BAG2 Antibody - C-terminal region (ARP42177_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "BAG2 Antibody - C-terminal region (ARP42177_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "BAG2 Antibody - C-terminal region (ARP42177_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "23kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "BAG2 Antibody - C-terminal region (ARP42177_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "BAG2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "BAG2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "BAG2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "BAG2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "BAG2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "BAG2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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