Size:100 ul
Special Price $229.00 Regular Price $249.00
In stock
SKU
ARP42177_T100
Request Bulk
Order Quote
Aviva's
Satisfaction
Guarantee
Contact Us:
  • Toll Free: (888)880-0001
  • Phone: (858)552-6979
  • Email: info@avivasysbio.com
Shipping Info:
  • $40: Antibody & Protein in US
  • $50: 1-2 Kits in US
  • Contact us for international orders.

Conjugation Options

ARP42177_T100-FITC Conjugated

ARP42177_T100-HRP Conjugated

ARP42177_T100-Biotin Conjugated

BAG2 Antibody - C-terminal region (ARP42177_T100)

Rating:
100% of 100
Catalog#: ARP42177_T100
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application IHC, WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-101216 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human BAG2
Purification Protein A purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Complete computational species homology data Anti-BAG2 (ARP42177_T100)
Peptide Sequence Synthetic peptide located within the following region: VDQKFQSIVIGCALEDQKKIKRRLETLLRNIENSDKAIKLLEHSKGAGSK
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-BAG2 (ARP42177_T100) antibody is Catalog # AAP42177 (Previous Catalog # AAPP24602)
Datasheets/Manuals Printable datasheet for anti-BAG2 (ARP42177_T100) antibody
Sample Type Confirmation

BAG2 is supported by BioGPS gene expression data to be expressed in Jurkat

Target Reference Arndt,V., (2005) Mol. Biol. Cell 16 (12), 5891-5900
Publications

Yue, X; Zhao, Y; Liu, J; Zhang, C; Yu, H; Wang, J; Zheng, T; Liu, L; Li, J; Feng, Z; Hu, W; BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function. 4, (2015). IHC, WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish 26271008

Gene Symbol BAG2
Official Gene Full Name BCL2-associated athanogene 2
Alias Symbols RP3-496N17.2, BAG-2, KIAA0576, MGC149462, dJ417I1.2
NCBI Gene Id 9532
Protein Name BAG family molecular chaperone regulator 2
Description of Target BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Swissprot Id O95816
Protein Accession # NP_004273
Nucleotide Accession # NM_004282
Protein Size (# AA) 211
Molecular Weight 23kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express BAG2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express BAG2.
Protein Interactions BAG2; UBC; TP53; LGALS3BP; TUBGCP2; TUBG1; STIP1; TAB1; STUB1; DNAJB6; MLF2; TTC1; STXBP2; SGTA; DNAJB1; HSPA8; SHFM1; PINK1; RPA3; RPA2; RPA1; AHNAK; PARK2; LATS2; TARDBP; EGFR; BAG3; HDAC11; SOX2; NPM1; PAN2; WDR83; WDR77; CCAR2; METTL21B; DNAJC6; NOS2;
Write Your Own Review
You're reviewing:BAG2 Antibody - C-terminal region (ARP42177_T100)
Your Rating