Catalog No: OAAB16244
Size:400ul
Price: $409.00
SKU
OAAB16244
Availability: Domestic: within 1 week delivery | International: 1 week
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for OAAB16244
Product Info
Predicted Species ReactivityHuman
Product FormatPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
ClonalityPolyclonal
IsotypeIg
HostRabbit
ApplicationDB
Additional InformationPrecautions: BAD Antibody (Phospho S57) is for research use only and not for use in diagnostic or therapeutic procedures.
::Function: Promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways
::Cellular Location: Mitochondrion outer membrane. Cytoplasm. Note=Upon phosphorylation, locates to the cytoplasm
Tissue Location: Expressed in a wide variety of tissues.
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S57 of human BAD.
Predicted Homology Based on Immunogen SequenceHuman
ConcentrationApproximately 0.5mg/ml. Actual concentration varies with each lot.
Application InfoDB: 1:500
Gene SymbolBAD
Alias SymbolsBBC2, BCL2L8
NCBI Gene Id572
Protein NameBcl2 antagonist of cell death
Description of TargetPeptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Uniprot IDQ92934
Protein Accession #NP_004313.1
Molecular Weight18392 Da
  1. What is the species homology for "BAD Antibody (Phospho-Ser57) (OAAB16244)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "BAD Antibody (Phospho-Ser57) (OAAB16244)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "BAD Antibody (Phospho-Ser57) (OAAB16244)" provided in?

    This item is provided in "Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "BAD Antibody (Phospho-Ser57) (OAAB16244)"?

    This target may also be called "BBC2, BCL2L8" in publications.

  5. What is the shipping cost for "BAD Antibody (Phospho-Ser57) (OAAB16244)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "BAD Antibody (Phospho-Ser57) (OAAB16244)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "BAD Antibody (Phospho-Ser57) (OAAB16244)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "18392 Da".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "BAD Antibody (Phospho-Ser57) (OAAB16244)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "BAD"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "BAD"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "BAD"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "BAD"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "BAD"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "BAD"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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