XRCC6 Antibody (Acetyl-Lys542) (OASG04124)

Catalog No: OASG04124

Size:100 uL

Western Blot using Jurkat

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC, ELISA
• Reconstitution and Storage: Store at -20°C for up to 1 year from date of receipt. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized acetyl-peptide derived from the human Ku-70 around the acetylation site of K542.
• Purification: The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Acetyl-Lys542
• Specificity: Acetyl-XRCC6-Lys542 polyclonal antibody (X-Ray Repair Cross-Complementing Protein 6) binds to endogenous X-Ray Repair Cross-Complementing Protein 6.
• Application Info: WB: 1:500~2000
  IHC: 1:100~300
  ELISA: 1:20000

Target Info

• Gene Symbol: XRCC6
• Gene Full Name: X-ray repair complementing defective repair in Chinese hamster cells 6
• Alias Symbols: ML8, KU70, TLAA, CTC75, CTCBF, G22P1
• NCBI Gene Id: 2547;
• Description of Target: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
• Uniprot ID: P12956
• Molecular Weight: 70 kDa