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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for anti-XRCC6 (OAAD00010) antibody |
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Predicted Species Reactivity | Human, Mouse, Monkey, Xenopus, Hamster |
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Product Format | Concentrated |
Clonality | Monoclonal |
Clone | N3H10 |
Isotype | IgG2b |
Host | Mouse |
Application | WB, IHC, IP, IF |
Reconstitution and Storage | Store at 2 - 8C for short term, freeze under -20C for long term storage |
Immunogen | Human placental extract designated as PSE1-PL |
Application Info | Immunofluorescence Immunoprecipitation (Native and denatured)(Use Protein A) (Ab 2ug/mg protein lysate) Western Blotting (0.25-0.5 ug/ml for 2hrs at RT) Immunohistology (Formalinparaffin)(Ab 1-2g/ml for 30 minute at RT) Staining of formalin-fixed tissues is IMPROVED by boiling tissue sections in 10mM citrate buffer, pH 6.0. THE OPTIMAL DILUTION SHOULD BE DETERMINED BY THE INDIVIDUAL LAB |
Reference | 1. Ajmani AK, et. al. Journal of Experimental Medicine, 1995, 181(6):2049-58. 2. Wang J, et. al. Molecular Biology Reports, 1993, 18(1):15-28. |
Gene Symbol | XRCC6 |
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Gene Full Name | X-ray repair cross-complementing protein 6 |
Alias Symbols | ML8, KU70, TLAA, CTC75, CTCBF, G22P1 |
NCBI Gene Id | 2547 |
Protein Name | X-ray repair cross-complementing protein 6 |
Description of Target | The Ku autoantigen is a heterodimer of 70kDa (p70) and - 80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis. |
Uniprot ID | P12956 |
Protein Accession # | NP_001275905.1; NP_001275906.1; NP_001460.1 |
Nucleotide Accession # | NM_001288976.1; NM_001288977.1; NM_001469.4 |
Molecular Weight | 70kD |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "XRCC6 Antibody (OAAD00010)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Monkey, Xenopus, Hamster".
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How long will it take to receive "XRCC6 Antibody (OAAD00010)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "XRCC6 Antibody (OAAD00010)" provided in?
This item is provided in "Concentrated".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "XRCC6 Antibody (OAAD00010)"?
This target may also be called "ML8, KU70, TLAA, CTC75, CTCBF, G22P1" in publications.
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What is the shipping cost for "XRCC6 Antibody (OAAD00010)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "XRCC6 Antibody (OAAD00010)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "XRCC6 Antibody (OAAD00010)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "70kD".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "XRCC6 Antibody (OAAD00010)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "XRCC6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "XRCC6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "XRCC6"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "XRCC6"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "XRCC6"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "XRCC6"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.