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VPS72 Antibody - N-terminal region (ARP74345_P050)

100 ul
$289.00
In Stock
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Conjugation Options

ARP74345_P050-FITC Conjugated

ARP74345_P050-HRP Conjugated

ARP74345_P050-Biotin Conjugated

Gene Symbol:
VPS72
NCBI Gene Id:
6944
Swissprot Id:
Q15906
Protein Accession #:
NP_005988.1
Alias Symbols:
TCFL1, YL1
Replacement Item:
This antibody may replace item sc-102155 from Santa Cruz Biotechnology.
Description of Target:
The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Protein Size (# AA):
364
Molecular Weight:
40 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express VPS72.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express VPS72.
Immunogen:
The immunogen is a synthetic peptide directed towards the N-terminal region of Human VPS72
Predicted Species Reactivity:
Human
Tested Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: GLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDE
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Blocking Peptide:
For anti-VPS72 (ARP74345_P050) antibody is Catalog # AAP74345
Datasheets/Manuals:
Printable datasheet for anti-VPS72 (ARP74345_P050) antibody
Target Reference:
N/A

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