| Product Number |
ARP74345_P050 |
| Product Page |
www.avivasysbio.com/vps72-antibody-n-terminal-region-arp74345-p050.html |
| Name |
VPS72 Antibody - N-terminal region (ARP74345_P050) |
| Protein Size (# AA) |
364 amino acids |
| Molecular Weight |
40 kDa |
| NCBI Gene Id |
6944 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Alias Symbols |
YL1, CFL1, Swc2, YL-1, TCFL1 |
| Peptide Sequence |
Synthetic peptide located within the following region: GLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
N/A |
| Description of Target |
The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms. |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-VPS72 (ARP74345_P050) antibody |
| Blocking Peptide |
For anti-VPS72 (ARP74345_P050) antibody is Catalog # AAP74345 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N-terminal region of Human VPS72 |
| Uniprot ID |
Q15906 |
| Protein Accession # |
NP_005988.1 |
| Purification |
Affinity purified |
| Tested Species Reactivity |
Human |
| Gene Symbol |
VPS72 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Image 1 | Human 786-0 Whole Cell
 | WB Suggested Anti-VPS72 antibody Titration: 1 ug/mL
Sample Type: Human 786-0 Whole Cell |
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