TXN Antibody - HRP Conjugated (OACA01001)

Catalog No: OACA01001

Size:100ug

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: HRP
• Application: Enzyme-linked immunosorbent assay
• Reconstitution and Storage: -20°C or -80°C
• Immunogen: Recombinant Human Thioredoxin protein (2-105AA)
• Purification: Protein G Purified
• Reference: [1] Nucleotide sequence of a cDNA encoding rat thioredoxin.'Tonissen K.F., Robins A.J., Wells J.R.E.Nucleic Acids Res. 17:3973-3973(1989)
  [2] Xie Z.H., Liu C.Z., He Y.H., Wang A.M., Ma C.
  [3] The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).'The MGC Project TeamGenome Res. 14:2121-2127(2004)
• Storage Buffer: Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Target Info

• Gene Symbol: TXN
• Gene Full Name: thioredoxin
• Alias Symbols: ADF;ATL-derived factor;SASP;surface-associated sulphydryl protein;testicular tissue protein Li 199;thioredoxin;thioredoxin delta 3;TRDX;TRX;TRX1;Trx80;TXN delta 3.
• NCBI Gene Id: 7295
• Protein Name: Thioredoxin
• Description of Target: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
• Uniprot ID: P10599