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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for OAAB06914 |
|---|
| Predicted Species Reactivity | Human, Mouse |
|---|---|
| Product Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Clonality | Monoclonal |
| Clone | 357CT4.4.2 |
| Isotype | IgG2b |
| Host | Mouse |
| Application | WB |
| Additional Information | Precautions: TSC1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| :: | Function: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling |
| :: | Cellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Note=At steady state found in association with membranes Tissue Location: Highly expressed in skeletal muscle, followed by heart, brain, placenta, pancreas, lung, liver and kidney. Also expressed in embryonic kidney cells |
| Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | Purified His-tagged TSC1 protein(Fragment) was used to produced this monoclonal antibody. |
| Predicted Homology Based on Immunogen Sequence | Human; Mouse |
| Concentration | Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Application Info | WB: 1:100~250 |
| Gene Symbol | TSC1 |
|---|---|
| Alias Symbols | LAM, TSC |
| NCBI Gene Id | 7248 |
| Protein Name | Hamartin |
| Description of Target | Mouse Monoclonal Antibody (Mab) |
| Uniprot ID | Q92574 |
| Protein Accession # | NP_000359.1 |
| Molecular Weight | 129767 Da |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "TSC1 Antibody (OAAB06914)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".
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How long will it take to receive "TSC1 Antibody (OAAB06914)"?
This item is available "Domestic: within 1 week delivery | International: 1 week".
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What buffer format is "TSC1 Antibody (OAAB06914)" provided in?
This item is provided in "Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "TSC1 Antibody (OAAB06914)"?
This target may also be called "LAM, TSC" in publications.
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What is the shipping cost for "TSC1 Antibody (OAAB06914)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "TSC1 Antibody (OAAB06914)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "TSC1 Antibody (OAAB06914)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "129767 Da".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "TSC1 Antibody (OAAB06914)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "TSC1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "TSC1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "TSC1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "TSC1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "TSC1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "TSC1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
