TRPM6 Antibody - middle region (OAAB17412)

Catalog No: OAAB17412

Size:400ul

CHAK2 Antibody (H332) (Cat. # OAAB17412) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CHAK2 antibody detected the CHAK2 protein (arrow).

TRPM6(CHAK2) Antibody (Center) (Cat. # OAAB17412) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRPM6 Antibody (CHAK2) (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid PBS with 0.09% (w/v) sodium azide
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC-P, ELISA
• Additional Information: Cellular Location: Membrane; Multi-pass membrane protein.
  Tissue Location: Highly expressed in kidney and colon. Isoform TRPM6a and isoform TRPM6b, are coexpressed with TRPM7 in kidney, and testis, and are also found in several cell lines of lung origin. Isoform TRPM6c is detected only in testis and in NCI-H510A small cell lung carcinoma cells
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This TRPM6 (CHAK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-348 amino acids from the Central region of human TRPM6 (CHAK2).
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: 0.5 mg/ml
• Intended Use: TRPM6 (CHAK2) Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
• Application Info: WB: 1:1000
  IHC-P: 1:10~50

Target Info

• Gene Symbol: TRPM6
• Alias Symbols: HSH, HMGX, HOMG, CHAK2, HOMG1
• NCBI Gene Id: 140803
• Protein Name: Transient receptor potential cation channel subfamily M member 6
• Description of Target: CHAK2 is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. It is also upregulated in certain forms of cancer and could play a role in diabetes.
• Uniprot ID: Q9BX84
• Protein Accession #: NP_001170781.1
• Molecular Weight: 232 kDa