TRPM6 Antibody - middle region (OAAB17412)

• Product Number: OAAB17412
• Name: TRPM6 Antibody - middle region (OAAB17412)
• Molecular Weight: 231708
• Isotype: Ig
• NCBI Gene Id: 140803
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: transient receptor potential cation channel subfamily M member 6
• Alias Symbols: CHAK2;channel kinase 2;HMGX;HOMG;HOMG1;HSH;melastatin-related TRP cation channel 6;transient receptor potential cation channel subfamily M member 6.
• Product Format: Liquid PBS with 0.09% (w/v) sodium azide
• Description of Target: Transient receptor potential cation channel subfamily M member 6, transient receptor potential cation channel subfamily M member 6 isoform a [Homo sapiens], transient receptor potential cation channel subfamily M member 6 isoform b [Homo sapiens], transient receptor potential cation channel subfamily M member 6 isoform c [Homo sapiens]
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Cellular Location: Membrane; Multi-pass membrane protein.
  Tissue Location: Highly expressed in kidney and colon. Isoform TRPM6a and isoform TRPM6b, are coexpressed with TRPM7 in kidney, and testis, and are also found in several cell lines of lung origin. Isoform TRPM6c is detected only in testis and in NCI-H510A small cell lung carcinoma cells
• Application Info: WB: 1:1000
  IHC-P: 1:10~50
• Immunogen: This TRPM6 (CHAK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-348 amino acids from the Central region of human TRPM6 (CHAK2).
• Intended Use: TRPM6 (CHAK2) Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
• Uniprot ID: https://www.uniprot.org/uniprot/Q9BX84
• Protein Name: NP_001170781.1, NP_001170782.1, NP_060132.3, Q9BX84
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_001170781.1,NP_001170782.1,NP_060132.3
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Gene Symbol: TRPM6
• Predicted Species Reactivity: Human
• Application: Immunohistochemistry-Paraffin, Western blot
• Image 1: Human kidney
  
  TRPM6(CHAK2) Antibody (Center) (Cat. # OAAB17412) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRPM6 Antibody (CHAK2) (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
• Image 2: CEM
  
  CHAK2 Antibody (H332) (Cat. # OAAB17412) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CHAK2 antibody detected the CHAK2 protein (arrow).