TRIP13 Antibody - C-terminal region (OAAB08917)

Catalog No: OAAB08917

Size:400ul

Western blot analysis of TRIP13 (arrow) using rabbit polyclonal TRIP13 Antibody (C-term) (Cat. #OAAB08917). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TRIP13 gene.

TRIP13 is strongly supported by BioGPS gene expression data to be expressed in HEK293

TRIP13 Antibody (C-term) (Cat. #OAAB08917)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRIP13 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

TRIP13 Antibody (C-term) (Cat. #OAAB08917) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Pig
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC, FC
• Additional Information: Precautions: TRIP13 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double- strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity)
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This TRIP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 363-392 amino acids from the C-terminal region of human TRIP13.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Pig; Rat
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  TRIP13 is strongly supported by BioGPS gene expression data to be expressed in HEK293

• Application Info: WB: 1:1000
  IHC-P: 1:10~50
  FC: 1:10~50

Target Info

• Gene Symbol: TRIP13
• Alias Symbols: MVA3, OOMD9, 16E1BP
• NCBI Gene Id: 9319
• Protein Name: Pachytene checkpoint protein 2 homolog
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q15645
• Protein Accession #: NP_004228.1
• Molecular Weight: 48551 Da