TNFSF14 Antibody - Biotin Conjugated (OACA01410)

Catalog No: OACA01410

Size:100ug

All lanes : Tumor necrosis factor ligand superfamily member 14 antibody at at 2 µg/ml
Lane 1 :EC109 whole cell lysate
Lane 2 :293T whole cell lysate
Secondary Goat polyclonal to Rabbit IgG at 1/15000 dilution
Predicted band size : 26 kDa
Observed band size: 45 kDa
Additional bands at :60 kDa. We are unsure as to the identity of this extra band.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Biotin
• Application: Enzyme-linked immunosorbent assay
• Reconstitution and Storage: -20°C or -80°C
• Immunogen: Recombinant Human Tumor necrosis factor ligand superfamily member 14 protein (1-239AA)
• Purification: Protein G Purified
• Purity: Caprylic Acid Ammonium Sulfate Precipitation
• Reference: [1] LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator.'Mauri D.N., Ebner R., Montgomery R.I., Kochel K.D., Cheung T.C., Yu G.-L., Ruben S., Murphy M., Eisenberg R.J., Cohen G.H., Spear P.G., Ware C.F.Immunity 8:21-30(1998)
  [2] Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth.'Harrop J.A., McDonnell P.C., Brigham-Burke M., Lyn S.D., Minton J., Tan K.B., Dede K., Spampanato J., Silverman C., Hensley P., DiPrinzio R., Emery J.G., Deen K., Eichman C., Chabot-Fletcher M., Truneh A., Young P.R.J. Biol. Chem. 273:27548-27556(1998)
  [3] Genomic characterization of LIGHT reveals linkage to an immune response locus on chromosome 19p13.3 and distinct isoforms generated by alternate splicing or proteolysis.'Granger S.W., Butrovich K.D., Houshmand P., Edwards W.R., Ware C.F.J. Immunol. 167:5122-5128(2001)
• Storage Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Target Info

• Gene Symbol: TNFSF14
• Gene Full Name: TNF superfamily member 14
• Alias Symbols: CD258;Herpes virus entry mediator ligand;herpesvirus entry mediator ligand;HVEML;LIGHT;LTg;tumor necrosis factor (ligand) superfamily, member 14;tumor necrosis factor ligand 1D;tumor necrosis factor ligand superfamily member 14;tumor necrosis factor superfamily member 14.
• NCBI Gene Id: 8740
• Protein Name: Tumor necrosis factor ligand superfamily member 14
• Description of Target: Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
• Uniprot ID: O43557