Size:100 ul
Special Price $229.00 Regular Price $289.00
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ARP87808_P050
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SESN1 Antibody - middle region (ARP87808_P050)

Catalog#: ARP87808_P050
Domestic: within 24 hours delivery | International: 3-5 business days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Human
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Immunogen The immunogen is a synthetic peptide directed towards the middle region of Human SESN1
Purification Affinity purified
Peptide Sequence Synthetic peptide located within the following region: ESMFVFSSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCW
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-SESN1 (ARP87808_P050) antibody is Catalog # AAP87808
Datasheets/Manuals Printable datasheet for anti-SESN1 (ARP87808_P050) antibody
Gene Symbol SESN1
Official Gene Full Name sestrin 1
Alias Symbols PA26, SEST1
NCBI Gene Id 27244
Protein Name sestrin-1
Description of Target This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Swissprot Id Q9Y6P5-2
Protein Accession # NP_001186862.1
Nucleotide Accession # NM_001199933.1
Protein Size (# AA) 551
Molecular Weight 60 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express SESN1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express SESN1.
  1. What is the species homology for "SESN1 Antibody - middle region (ARP87808_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "SESN1 Antibody - middle region (ARP87808_P050)"?

    This item is available "Domestic: within 24 hours delivery | International: 3-5 business days".

  3. What buffer format is "SESN1 Antibody - middle region (ARP87808_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SESN1 Antibody - middle region (ARP87808_P050)"?

    This target may also be called "PA26, SEST1" in publications.

  5. What is the shipping cost for "SESN1 Antibody - middle region (ARP87808_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SESN1 Antibody - middle region (ARP87808_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SESN1 Antibody - middle region (ARP87808_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "60 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SESN1 Antibody - middle region (ARP87808_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "SESN1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SESN1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SESN1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SESN1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SESN1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SESN1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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