SBDS Protein (OPPA02486)

Catalog No: OPPA02486 (Formerly GWB-BSP644)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: The SBDS protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0) 2mM DTT, 50mM NaCl, 0.1mM EDTA, and 20% glycerol. Physical appearance: Sterile Filtered clear solution.
• Host: E. Coli
  Product Introduction: SBDS is part of an extremely preserved protein family which exists from archaea to vertebrates and plants. SBDS protein functions in RNA metabolism and has a role in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Shwachman-Diamond syndrome is a rare autosomal recessive disorder produced by mutations in the SBDS gene.
  Product Description: SBDS produced in E.Coli is a single, non-glycosylated polypeptide chain containing 270 amino acids (1-250a.a.) and having a molecular mass of 30.9kDa.SBDS is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
• Reconstitution and Storage: Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time.Please avoid freeze thaw cycles.
• Purity: Greater than 95% as determined by SDS-PAGE.
• Peptide Sequence: MGSSHHHHHH SSGLVPRGSH MSIFTPTNQI RLTNVAVVRM KRAGKRFEIA CYKNKVVGWR SGVEKDLDEV LQTHSVFVNV SKGQVAKKED LISAFGTDDQ TEICKQILTK GEVQVSDKER HTQLEQMFRD IATIVADKCV NPETKRPYTV ILIERAMKDI HYSVKTNKST KQQALEVIKQ LKEKMKIERA HMRLRFILPV NEGKKLKEKL KPLIKVIESE DYGQQLEIVC LIDPGCFREI DELIKKETKG KGSLEVLNLK DVEEGDEKFE

Target Info

• Gene Symbol: SBDS
• Alias Symbols: SDS, SDO1, SWDS, CGI-97
• NCBI Gene Id: 51119
• Protein Name: Ribosome maturation protein SBDS
• Description of Target: Recombinant Human Shwachman-Bodian-Diamond Syndrome
• Uniprot ID: Q9Y3A5
• Protein Accession #: NP_057122.2
• Protein Size (# AA): Recombinant