Size:100 ul
Special Price $229.00 Regular Price $249.00
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ARP45719_T100
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Conjugation Options

ARP45719_T100-FITC Conjugated

ARP45719_T100-HRP Conjugated

ARP45719_T100-Biotin Conjugated

SBDS Antibody - N-terminal region (ARP45719_T100)

Catalog#: ARP45719_T100
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application IHC, WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-134735 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SBDS
Purification Protein A purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 85%
Complete computational species homology data Anti-SBDS (ARP45719_T100)
Peptide Sequence Synthetic peptide located within the following region: LQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKER
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-SBDS (ARP45719_T100) antibody is Catalog # AAP45719 (Previous Catalog # AAPP11852)
Datasheets/Manuals Printable datasheet for anti-SBDS (ARP45719_T100) antibody
Target Reference Austin,K.M., (2005) Blood 106 (4), 1253-1258
Publications

Sezgin, G. et al. Impaired growth, hematopoietic colony formation, and ribosome maturation in human cells depleted of Shwachman-Diamond syndrome protein SBDS. Pediatr. Blood Cancer 60, 281-6 (2013). IHC, WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish 22997148

Gene Symbol SBDS
Official Gene Full Name Shwachman-Bodian-Diamond syndrome
Alias Symbols CGI-97, FLJ10917, SDS, SWDS
NCBI Gene Id 51119
Protein Name Ribosome maturation protein SBDS
Description of Target SBDS is a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The protein may function in RNA metabolism. Mutations within its gene are associated with Shwachman-Bodian-Diamond syndrome.This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located.
Swissprot Id Q9Y3A5
Protein Accession # NP_057122
Nucleotide Accession # NM_016038
Protein Size (# AA) 250
Molecular Weight 28kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express SBDS.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express SBDS.
Protein Interactions SUMO2; TYMS; PNP; IDH1; GOT1; UBC; CHAMP1; MPLKIP; MRPL53; SARNP; SLIRP; SRPRB; ACOT13; SRRM2; TIMM44; TOMM40; UBE4B; SCO2; SNX3; STX7; SF1; VDAC3; TIAL1; SPR; RBMS1; NDUFA7; NDUFA2; IDH3G; STOM; ACAA1; ACD; TERF2IP; POT1; TERF1; CLN3;
  1. What is the species homology for "SBDS Antibody - N-terminal region (ARP45719_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish".

  2. How long will it take to receive "SBDS Antibody - N-terminal region (ARP45719_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "SBDS Antibody - N-terminal region (ARP45719_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SBDS Antibody - N-terminal region (ARP45719_T100)"?

    This target may also be called "CGI-97, FLJ10917, SDS, SWDS" in publications.

  5. What is the shipping cost for "SBDS Antibody - N-terminal region (ARP45719_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SBDS Antibody - N-terminal region (ARP45719_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SBDS Antibody - N-terminal region (ARP45719_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "28kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SBDS Antibody - N-terminal region (ARP45719_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "SBDS"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SBDS"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SBDS"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SBDS"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SBDS"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SBDS"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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