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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for anti-PTTG1 (OAAJ01951) antibody |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB, IF, ICC |
| Reconstitution and Storage | Store at -20C. Stable for 12 months from date of receipt. |
| Immunogen | A synthesized peptide derived from human PTTG1 |
| Purification | Affinity-chromatography |
| Concentration | 1 mg/ml |
| Specificity | PTTG1 antibody detects endogenous levels of total PTTG1 |
| Application Info | WB: 1:500~1:3000 IF/ICC: 1:100~1:500 |
| Gene Symbol | PTTG1 |
|---|---|
| Gene Full Name | pituitary tumor-transforming 1 |
| Alias Symbols | EAP1, PTTG, HPTTG, TUTR1 |
| NCBI Gene Id | 9232 |
| Description of Target | securin Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1. Its function is however not limited to a blocking activity, since it is required to activate ESPL1. Negatively regulates the transcriptional activity and related apoptosis activity of TP53. |
| Uniprot ID | O95997 |
| Molecular Weight | 30 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PTTG1 Antibody (OAAJ01951)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "PTTG1 Antibody (OAAJ01951)"?
This item is available "Domestic: within 2-3 week delivery | International: 2-3 weeks".
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What buffer format is "PTTG1 Antibody (OAAJ01951)" provided in?
This item is provided in "Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PTTG1 Antibody (OAAJ01951)"?
This target may also be called "EAP1, PTTG, HPTTG, TUTR1" in publications.
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What is the shipping cost for "PTTG1 Antibody (OAAJ01951)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PTTG1 Antibody (OAAJ01951)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PTTG1 Antibody (OAAJ01951)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "30 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PTTG1 Antibody (OAAJ01951)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PTTG1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PTTG1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PTTG1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PTTG1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PTTG1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PTTG1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
