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- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for PTTG1 Antibody (OAAL00445) |
|---|
| Predicted Species Reactivity | Human, Mouse |
|---|---|
| Product Format | Liquid |
| Clonality | Monoclonal |
| Clone | 3F9 |
| Isotype | IgG2a Kappa |
| Host | Mouse |
| Application | Enzyme-linked immunosorbent assay|Immunofluorescence |
| Reconstitution and Storage | Store at -20C or lower. Aliquot to avoid repeated freezing and thawing. |
| Immunogen | PTTG1 (NP_004210, 93 a.a. ~ 113 a.a) synthetic peptide. |
| Peptide Sequence | CKTVKAKSSVPASD |
| Formulation | In 1x PBS, pH 7.4 |
| Gene Symbol | PTTG1 |
|---|---|
| Gene Full Name | PTTG1 regulator of sister chromatid separation, securin |
| Alias Symbols | EAP1;ESP1-associated protein 1;HPTTG;pituitary tumor-transforming 1;pituitary tumor-transforming gene 1 protein;PTTG;securin;tumor-transforming protein 1;TUTR1. |
| NCBI Gene Id | 9232 |
| Protein Name | Homo sapiens pituitary tumor-transforming 1 (PTTG1), transcript variant 2, mRNA|securin [Homo sapiens] |
| Description of Target | The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. [provided by RefSeq |
| Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_004210 |
| Nucleotide Accession # | https://www.ncbi.nlm.nih.gov/nuccore/NM_004219 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PTTG1 Antibody (OAAL00445)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".
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How long will it take to receive "PTTG1 Antibody (OAAL00445)"?
This item is available "Domestic: within 2-3 week delivery | International: 2-3 weeks".
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What buffer format is "PTTG1 Antibody (OAAL00445)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PTTG1 Antibody (OAAL00445)"?
This target may also be called "EAP1;ESP1-associated protein 1;HPTTG;pituitary tumor-transforming 1;pituitary tumor-transforming gene 1 protein;PTTG;securin;tumor-transforming protein 1;TUTR1." in publications.
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What is the shipping cost for "PTTG1 Antibody (OAAL00445)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PTTG1 Antibody (OAAL00445)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PTTG1 Antibody (OAAL00445)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PTTG1 Antibody (OAAL00445)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PTTG1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PTTG1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PTTG1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PTTG1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PTTG1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PTTG1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
