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PTGS1 Antibody (OAGA04261)

100 ul
$409.00
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Gene Symbol:
PTGS1
Official Gene Full Name:
prostaglandin-endoperoxide synthase 1
NCBI Gene Id:
5742
Protein Name:
prostaglandin G/H synthase 1
Swissprot Id:
P23219
Protein Accession #:
NP_000953.2
Nucleotide Accession #:
NM_000962.3
Alias Symbols:
COX1, COX3, PHS1, PCOX1, PES-1, PGHS1, PTGHS, PGG/HS, PGHS-1
Description of Target:
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Purified by antigen-affinity chromatography.
Application:
IHC-P, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PTGS1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express PTGS1.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human COX1. The exact sequence is proprietary.
Product Format:
Liquid
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Concentration:
0.68 mg/ml
Datasheets/Manuals:
Printable datasheet for OAGA04261
Preservative:
0.01% Thimerosal
Isotype:
IgG
Application Info:
Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer:
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

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