| Product Number |
OAGA04261 |
| Product Page |
www.avivasysbio.com/ptgs1-antibody-oaga04261.html |
| Name |
PTGS1 Antibody (OAGA04261) |
| Isotype |
IgG |
| NCBI Gene Id |
5742 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.68 mg/ml |
| Gene Full Name |
prostaglandin-endoperoxide synthase 1 |
| Alias Symbols |
COX1, COX3, PHS1, PCOX1, PES-1, PGHS1, PTGHS, PGG/HS, PGHS-1 |
| Product Format |
Liquid |
| Description of Target |
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. |
| Reconstitution and Storage |
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAGA04261 |
| Application Info |
Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human COX1. The exact sequence is proprietary. |
| Storage Buffer |
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Uniprot ID |
P23219 |
| Protein Name |
prostaglandin G/H synthase 1 |
| Protein Accession # |
NP_000953.2 |
| Purification |
Purified by antigen-affinity chromatography. |
| Nucleotide Accession # |
NM_000962.3 |
| Preservative |
0.01% Thimerosal |
| Gene Symbol |
PTGS1 |
| Predicted Species Reactivity |
Human, Mouse, Rat |
| Application |
IHC-P, WB |
| Image 1 | H1299 xenograft
 | COX1 antibody detects PTGS1 protein at cytosol on by immunohistochemical analysis.
Sample: Paraffin-embedded H1299 xenograft.
COX1 antibody dilution: 1:500.
|
| | Image 2 | Mouse brain extract
 | COX1 antibody detects COX1 protein by western blot analysis.
A. 50 ug mouse brain extract
7.5 % SDS-PAGE
COX1 antibody dilution: 1:1000 |
| | Image 3 | Rat brain extract
 | COX1 antibody detects COX1 protein by western blot analysis.
A. 50 ug rat brain extract
7.5 % SDS-PAGE
COX1 antibody dilution: 1:1000 |
| | Image 4 | Molt-4
 | Sample (30 ug of whole cell lysate)
A: Molt-4
7.5% SDS PAGE
diluted at 1:1000
|
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