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| Datasheets/Manuals | Printable datasheet for OAAB07039 |
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| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Clonality | Monoclonal |
| Clone | 487CT6.9.2 |
| Isotype | IgG1 |
| Host | Mouse |
| Application | WB |
| Additional Information | Precautions: NOTCH3 Antibody (C-term Q2306) is for research use only and not for use in diagnostic or therapeutic procedures. |
| :: | Function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity) |
| :: | Cellular Location: Cell membrane; Single-pass type I membrane protein Tissue Location: Ubiquitously expressed in fetal and adult tissues |
| Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | This NOTCH3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 2291-2321 amino acids from the C-terminal region of human NOTCH3. |
| Predicted Homology Based on Immunogen Sequence | Human |
| Concentration | Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Application Info | WB: 1:2000 WB: 1:100~250 |
| Gene Symbol | NOTCH3 |
|---|---|
| Alias Symbols | IMF2, LMNS, CASIL, CADASIL, CADASIL1 |
| NCBI Gene Id | 4854 |
| Protein Name | Neurogenic locus notch homolog protein 3 |
| Description of Target | Mouse Monoclonal Antibody (Mab) |
| Uniprot ID | Q9UM47 |
| Protein Accession # | NP_000426.2 |
| Molecular Weight | 243631 Da |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "NOTCH3 Antibody - C-terminal region (OAAB07039)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "NOTCH3 Antibody - C-terminal region (OAAB07039)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "NOTCH3 Antibody - C-terminal region (OAAB07039)" provided in?
This item is provided in "Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "NOTCH3 Antibody - C-terminal region (OAAB07039)"?
This target may also be called "IMF2, LMNS, CASIL, CADASIL, CADASIL1" in publications.
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What is the shipping cost for "NOTCH3 Antibody - C-terminal region (OAAB07039)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "NOTCH3 Antibody - C-terminal region (OAAB07039)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "NOTCH3 Antibody - C-terminal region (OAAB07039)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "243631 Da".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "NOTCH3 Antibody - C-terminal region (OAAB07039)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "NOTCH3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "NOTCH3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "NOTCH3"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "NOTCH3"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "NOTCH3"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "NOTCH3"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
