NOG Recombinant Protein (OPCD05709)

Catalog No: OPCD05709

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Gln28-Cys232
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: NOG
• Gene Full Name: noggin
• Alias Symbols: noggin;SYM1;symphalangism 1 (proximal);SYNS1;SYNS1A.
• NCBI Gene Id: 9241
• Protein Name: Noggin
• Description of Target: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (PubMed:21976273, PubMed:26643732).
• Uniprot ID: Q13253
• Protein Accession #: NP_005441.1
• Nucleotide Accession #: NM_005450.4
• Protein Size (# AA): Gln28~Cys232
• Molecular Weight: 24kDa