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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for NF2 Antibody (OACD05956) |
|---|
| Predicted Species Reactivity | Human|Mouse |
|---|---|
| Product Format | Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot |
| Reconstitution and Storage | 2°C to 8°C|-20°C |
| Immunogen | Recombinant NF2 (Asp30~Leu239) expressed in E.coli. |
| Purification | Affinity Purified; Protein A Purified |
| Concentration | 0.5 mg/ml |
| Specificity | The antibody is a rabbit polyclonal antibody raised against NF2. It has been selected for its ability to recognize NF2 in immunohistochemical staining and western blotting. |
| Application Data | WB: 0.5-2 ug/mL IHC: 5-20 ug/mL ICC: 5-20 ug/mL |
| Gene Symbol | NF2 |
|---|---|
| Gene Full Name | neurofibromin 2 |
| Alias Symbols | ACN;BANF;bilateral acoustic neurofibromatosis;merlin;merlin-1;moesin-ezrin-radixin like;moesin-ezrin-radixin-like protein;moesin-ezrin-radizin-like protein;neurofibromin 2 (bilateral acoustic neuroma);Neurofibromin-2;SCH;schwannomerlin;schwannomin. |
| NCBI Gene Id | 4771 |
| Protein Name | Merlin |
| Description of Target | Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex. |
| Uniprot ID | P35240 |
| Protein Accession # | NP_000259.1 |
| Nucleotide Accession # | NM_000268 |
| Molecular Weight | 19 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "NF2 Antibody (OACD05956)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "NF2 Antibody (OACD05956)"?
This item is available "Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery".
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What buffer format is "NF2 Antibody (OACD05956)" provided in?
This item is provided in "Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "NF2 Antibody (OACD05956)"?
This target may also be called "ACN;BANF;bilateral acoustic neurofibromatosis;merlin;merlin-1;moesin-ezrin-radixin like;moesin-ezrin-radixin-like protein;moesin-ezrin-radizin-like protein;neurofibromin 2 (bilateral acoustic neuroma);Neurofibromin-2;SCH;schwannomerlin;schwannomin." in publications.
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What is the shipping cost for "NF2 Antibody (OACD05956)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "NF2 Antibody (OACD05956)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "NF2 Antibody (OACD05956)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "19 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "NF2 Antibody (OACD05956)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "NF2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "NF2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "NF2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "NF2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "NF2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "NF2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
