Size:100 ul
Special Price $229.00 Regular Price $319.00
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ARP63180_P050
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Conjugation Options

ARP63180_P050-FITC Conjugated

ARP63180_P050-HRP Conjugated

ARP63180_P050-Biotin Conjugated

NF2 Antibody - C-terminal region (ARP63180_P050)

Catalog#: ARP63180_P050
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-172383 from Santa Cruz Biotechnology.
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Complete computational species homology data Anti-NF2 (ARP63180_P050)
Peptide Sequence Synthetic peptide located within the following region: MAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPA
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-NF2 (ARP63180_P050) antibody is Catalog # AAP63180
Datasheets/Manuals Printable datasheet for anti-NF2 (ARP63180_P050) antibody
Publications

Vasilyeva, NA; Murzina, GB; Kireev, II; Pivovarov, AS; Influence of Membrane Receptor Lateral Diffusion on the Short-Term Depression of Acetylcholine-Induced Current in Helix Neurons. , (2017). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish 28236056

Gene Symbol NF2
Official Gene Full Name Neurofibromin 2 (merlin)
Alias Symbols ACN, BANF, SCH
NCBI Gene Id 4771
Protein Name Merlin
Description of Target This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.
Swissprot Id P35240-4
Protein Accession # NP_861968
Nucleotide Accession # NM_181830
Protein Size (# AA) 507
Molecular Weight 56kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express NF2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express NF2.
Protein Interactions VPRBP; CD44; UBC; KDM1A; AMOTL2; YAP1; PPP1R8; UBD; CCNB1IP1; HGS; CUL4A; DDB1; GPS1; WWC1; PYGO2; AMOT; SCHIP1; SGSM3; NF2; TSC1; TARBP2; SLC9A3R1; PAK1; XPO1; PXN; SDCBP; RALGDS; SPTBN1; ERBB2; ITGB1; EZR; CTNNB1; AGAP2; AKT1; RIT1; ARHGAP32; SOS1; MED2
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