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Conjugation Options

OAAF00358-FITC Conjugated

OAAF00358-HRP Conjugated

OAAF00358-Biotin Conjugated

mTOR Antibody (Phospho-Ser2448) (OAAF00358)

Catalog#: OAAF00358
This product is Genway GWB-ASB743
More Information
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
ApplicationWB, IHC
::Modification Sites: H:S2448 M:S2448 R:S2448
Reconstitution and StorageStore at -20C/1 year
Replacement ItemThis antibody may replace item sc-101738 from Santa Cruz Biotechnology.
ImmunogenThe antiserum was produced against synthesized peptide derived between 2415-2464 amino acids from the C-Terminal region of human mTOR around the phosphorylation site of Ser2448.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Datasheets/ManualsPrintable datasheet for OAAF00358
SpecificitymTOR (phospho-Ser2448) antibody detects endogenous levels of mTOR only when phosphorylated at serine 2448.
DilutionThe optimal working dilution should be determined by the end user.
Intended UseThe product is for research use only, not for use in diagnostic or therapeutic procedures.
Application InfoWB: 1:500~1000
IHC: 1:50~100
ELISA: 1:40000
Target Referenceherine M. Hannan, Mol. Cell. Biol., Dec 2003; 23: 8862 - 8877.
Dos D. Sarbassov, Science, Feb 2005; 307: 1098 - 1101.
Susan W. Y. Cheng, J. Biol. Chem., Apr 2004; 279: 15719 - 15722.
Charles H. Lang, Am J Physiol Endocrinol Metab, Dec 2003; 28
Gene SymbolmTOR
Official Gene Full NameSerine/threonine-protein kinase mTOR
Alias SymbolsFRAP, FRAP1, FRAP2, RAFT1, RAPT1,
NCBI Gene Id2475
Protein NameSerine/threonine-protein kinase mTOR
Swissprot IdP42345
Protein Accession #NP_004949.1
Molecular Weight288 kDa
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express mTOR.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express mTOR.
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