MGMT Recombinant Protein (OPCD05238)

Catalog No: OPCD05238

MGMT Recombinant Protein (OPCD05238) using SDS-PAGE

MGMT Recombinant Protein (OPCD05238) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Rat|Rattus norvegicus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-Gly209
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His and GST Tag

Target Info

• Gene Symbol: Mgmt
• Gene Full Name: O-6-methylguanine-DNA methyltransferase
• Alias Symbols: 0-6-methylguanine-DNA methyltransferase;6-O-methylguanine-DNA methyltransferase;methylated-DNA--protein-cysteine methyltransferase;O(6)-alkylguanine-DNA alkyltransferase;O6-alkylguanine-DNA alkyltransferase;O6-methylguanine-DNA methyltranferase;O-6-methylguanine-DNA-alkyltransferase.
• NCBI Gene Id: 25332
• Protein Name: Methylated-DNA--protein-cysteine methyltransferase
• Description of Target: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
• Uniprot ID: P24528
• Protein Accession #: NP_036993.1
• Nucleotide Accession #: NM_012861.1
• Protein Size (# AA): Met1~Gly209
• Molecular Weight: 52kDa