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| Datasheets/Manuals | Printable datasheet for ME2 Antibody - N-terminal (OAPB01874) (OAPB01874) |
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| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid. ME2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | ME2 antibody was raised against a 17 amino acid peptide near the center of human ME2. The immunogen is located within amino acids 340 - 390 of ME2. |
| Purification | Affinity Purified |
| Concentration | 1 mg/ml |
| Gene Symbol | ME2 |
|---|---|
| Gene Full Name | malic enzyme 2 |
| Alias Symbols | malate dehydrogenase (oxaloacetate-decarboxylating);Malic enzyme 2;malic enzyme 2, NAD(+)-dependent, mitochondrial;NAD-dependent malic enzyme, mitochondrial;NAD-ME;ODS1;pyruvic-malic carboxylase. |
| NCBI Gene Id | 4200 |
| Protein Name | NAD-dependent malic enzyme, mitochondrial|NAD-dependent malic enzyme, mitochondrial isoform 1 precursor [Homo sapiens] |
| Description of Target | ME2 is a homotetrameric, mitochondrial NAD-dependent malic enzyme that catalyzes the oxidative decarboxylation of malate to pyruvate (1). It is related to malic enzyme 1 (ME1), a cytoplasmic NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis (2). The expression of both malic enzymes is reciprocally regulated by p53; this regulation has been shown to modulate metabolism and senescence (3). Certain single-nucleotide polymorphism haplotypes of the ME2 gene have been shown to increase the risk for idiopathic generalized epilepsy (4). |
| Uniprot ID | P23368 |
| Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_002387 |
| Nucleotide Accession # | NM_001168335.1 |
| Molecular Weight | Predicted: 64 kDa Observed: 60 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ME2 Antibody - N-terminal (OAPB01874)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "ME2 Antibody - N-terminal (OAPB01874)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "ME2 Antibody - N-terminal (OAPB01874)" provided in?
This item is provided in "Liquid. ME2 Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ME2 Antibody - N-terminal (OAPB01874)"?
This target may also be called "malate dehydrogenase (oxaloacetate-decarboxylating);Malic enzyme 2;malic enzyme 2, NAD(+)-dependent, mitochondrial;NAD-dependent malic enzyme, mitochondrial;NAD-ME;ODS1;pyruvic-malic carboxylase." in publications.
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What is the shipping cost for "ME2 Antibody - N-terminal (OAPB01874)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ME2 Antibody - N-terminal (OAPB01874)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ME2 Antibody - N-terminal (OAPB01874)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "Predicted: 64 kDa Observed: 60 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ME2 Antibody - N-terminal (OAPB01874)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ME2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ME2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ME2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ME2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ME2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ME2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
