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MANBA Antibody (OAGA00216)

100 ul
$409.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
WB
Additional Information:
Background: This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. [provided by RefSeq]
:::
Positive Controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji
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Cellular Localization: Lysosome
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Gene Symbol:
MANBA
Official Gene Full Name:
Beta-mannosidase
NCBI Gene Id:
4126
Protein Name:
Beta-mannosidase
Swissprot Id:
O00462
Protein Accession #:
NP_005899.3
Alias Symbols:
MANB1 antibody, MANBA antibody, lysosomal beta A mannosidase antibody, mannase antibody, beta-mannosidase antibody, mannanase antibody, "mannosidase, beta A, lysosomal antibody"
Replacement Item:
This antibody may replace item sc-149247 from Santa Cruz Biotechnology.
Molecular Weight:
101 kDa
Purification:
Purified by antigen-affinity chromatography.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MANBA.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MANBA.
Immunogen:
Recombinant fragment corresponding to a region within amino acids 380 and 654 of MANBA (Uniprot ID#O00462)
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-MANBA antibody - OAGA00216
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer:
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

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