MANBA Antibody (OAGA00216)

Catalog No: OAGA00216

Size:100 ul

Sample(30 ?g of whole cell lysate)
A:Hep G2
7.5% SDS PAGE
OAGA00216 diluted at 1:500

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Additional Information: Background: This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. [provided by RefSeq]
  Positive Controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji
  Cellular Localization: Lysosome
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant fragment corresponding to a region within amino acids 380 and 654 of MANBA (Uniprot ID#O00462)
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: MANBA
• Gene Full Name: Beta-mannosidase
• Alias Symbols: MANB1
• NCBI Gene Id: 4126
• Protein Name: Beta-mannosidase
• Uniprot ID: O00462
• Protein Accession #: NP_005899.3
• Molecular Weight: 101 kDa