| Product Number |
OAGA00216 |
| Product Page |
www.avivasysbio.com/manba-antibody-oaga00216.html |
| Name |
MANBA Antibody (OAGA00216) |
| Molecular Weight |
101 kDa |
| Isotype |
IgG |
| NCBI Gene Id |
4126 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 mg/ml |
| Gene Full Name |
Beta-mannosidase |
| Alias Symbols |
MANB1 |
| Product Format |
Liquid |
| Reconstitution and Storage |
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MANBA antibody - OAGA00216 |
| Additional Information |
Background: This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. [provided by RefSeq] |
| Additional Information |
Positive Controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji |
| Application Info |
Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Immunogen |
Recombinant fragment corresponding to a region within amino acids 380 and 654 of MANBA (Uniprot ID#O00462) |
| Additional Information |
Cellular Localization: Lysosome |
| Storage Buffer |
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Uniprot ID |
O00462 |
| Protein Name |
Beta-mannosidase |
| Protein Accession # |
NP_005899.3 |
| Purification |
Purified by antigen-affinity chromatography. |
| Gene Symbol |
MANBA |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Image 1 | HepG2
 | Sample(30 ?g of whole cell lysate)
A:Hep G2
7.5% SDS PAGE
OAGA00216 diluted at 1:500 |
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