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Datasheets/Manuals | Printable datasheet for KCNMA1 Antibody (OACA04701) (OACA04701) |
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Predicted Species Reactivity | Human |
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Product Format | Liquid |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry |
Reconstitution and Storage | -20°C or -80°C |
Immunogen | Recombinant Human Calcium-activated potassium channel subunit alpha-1 protein (1-86AA) |
Purification | Protein G Purified |
Preservative | 0.03% Proclin 300 |
Formulation | 50% Glycerol, 0.01M PBS, PH 7.4 |
Purity | >95% |
Gene Symbol | KCNMA1 |
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Gene Full Name | potassium calcium-activated channel subfamily M alpha 1 |
Alias Symbols | bA205K10.1;big potassium channel alpha subunit;BK channel;BK channel alpha subunit;BKCA alpha;BKCA alpha subunit;BKTM;CADEDS;Calcium-activated potassium channel subunit alpha-1;calcium-activated potassium channel, subfamily M subunit alpha-1;hSlo;IEG16;k(VCA)alpha;KCa1.1;LIWAS;Maxi K channel;MaxiK;maxi-K channel HSLO;mSLO1;PNKD3;potassium channel, calcium activated large conductance subfamily M alpha, member 1;potassium large conductance calcium-activated channel, subfamily M, alpha member 1;SAKCA;SLO;slo homolog;SLO1;SLO-ALPHA;slowpoke homolog;stretch-activated Kca channel. |
NCBI Gene Id | 3778 |
Protein Name | Calcium-activated potassium channel subunit alpha-1 |
Description of Target | Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential. In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map. Kinetics of KCNMA1 channels are determined by alternative splicing, phosphorylation status and its combination with modulating beta subunits. Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX). |
Uniprot ID | Q12791 |
Protein Accession # | NP_001014797 |
Nucleotide Accession # | NM_001014797 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "KCNMA1 Antibody (OACA04701)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "KCNMA1 Antibody (OACA04701)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "KCNMA1 Antibody (OACA04701)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "KCNMA1 Antibody (OACA04701)"?
This target may also be called "bA205K10.1;big potassium channel alpha subunit;BK channel;BK channel alpha subunit;BKCA alpha;BKCA alpha subunit;BKTM;CADEDS;Calcium-activated potassium channel subunit alpha-1;calcium-activated potassium channel, subfamily M subunit alpha-1;hSlo;IEG16;k(VCA)alpha;KCa1.1;LIWAS;Maxi K channel;MaxiK;maxi-K channel HSLO;mSLO1;PNKD3;potassium channel, calcium activated large conductance subfamily M alpha, member 1;potassium large conductance calcium-activated channel, subfamily M, alpha member 1;SAKCA;SLO;slo homolog;SLO1;SLO-ALPHA;slowpoke homolog;stretch-activated Kca channel." in publications.
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What is the shipping cost for "KCNMA1 Antibody (OACA04701)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "KCNMA1 Antibody (OACA04701)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "KCNMA1 Antibody (OACA04701)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "KCNMA1 Antibody (OACA04701)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "KCNMA1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "KCNMA1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "KCNMA1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "KCNMA1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "KCNMA1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "KCNMA1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.