Size:400ul
$329.00
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OAAB08672
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I23O2 Antibody - C-terminal region (OAAB08672)

Catalog#: OAAB08672
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species Reactivity Human
Product Format LiquidPBS with 0.09% (W/V) sodium azide.
Clonality Polyclonal
Isotype Ig
Host Rabbit
Application WB, IHC-P
Additional Information Function: Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in immune regulation. May not play a significant role in tryptophan-related tumoral resistance.
Tissue Location: Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon. Also expressed at low level in testis and thyroid. Not expressed in the majority of human tumor samples (>99%).
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-292211 from Santa Cruz Biotechnology.
Immunogen This I23O2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-295 amino acids from the C-terminal region of human I23O2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration 0.5 mg/ml
Datasheets/Manuals Printable datasheet for OAAB08672
Intended Use I23O2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Application Info IHC-P: 1:10~50
WB: 1:1000
Optimal dilutions should be determined by the end user.
Target Reference Cetindere, T., et al. Cell. Signal. 22(2):197-211(2010)
Huttunen, R., et al. Shock 33(2):149-154(2010)
Witkiewicz, A.K., et al. J. Am. Coll. Surg. 208(5):781-787(2009)
Metz, R., et al. Cancer Res. 67(15):7082-7087(2007)
Ball, H.J., et al. Gene 396(1):203-213(2007)
Gene Symbol IDO2
Alias Symbols Indoleamine 2, 3-dioxygenase 2, IDO-2, 11311-, Indoleamine 2, 3-dioxygenase-like protein 1, Indoleamine-pyrrole 2, 3-dioxygenase-like protein 1, IDO2, INDOL1
NCBI Gene Id 169355
Protein Name Indoleamine 2,3-dioxygenase 2
Description of Target Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway.
Swissprot Id Q6ZQW0
Protein Accession # NP_919270.2
Molecular Weight 47 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express IDO2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express IDO2.
  1. What is the species homology for "I23O2 Antibody - C-terminal region (OAAB08672)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "I23O2 Antibody - C-terminal region (OAAB08672)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "I23O2 Antibody - C-terminal region (OAAB08672)" provided in?

    This item is provided in "LiquidPBS with 0.09% (W/V) sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "I23O2 Antibody - C-terminal region (OAAB08672)"?

    This target may also be called "Indoleamine 2, 3-dioxygenase 2, IDO-2, 11311-, Indoleamine 2, 3-dioxygenase-like protein 1, Indoleamine-pyrrole 2, 3-dioxygenase-like protein 1, IDO2, INDOL1" in publications.

  5. What is the shipping cost for "I23O2 Antibody - C-terminal region (OAAB08672)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "I23O2 Antibody - C-terminal region (OAAB08672)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "I23O2 Antibody - C-terminal region (OAAB08672)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "47 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "I23O2 Antibody - C-terminal region (OAAB08672)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "IDO2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "IDO2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "IDO2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "IDO2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "IDO2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "IDO2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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