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HIST1H1C Antibody - middle region (ARP46122_P050)

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100 ul

Regular Price: $319.00

Special Price: $229.00

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Conjugation Options

ARP46122_P050-FITC Conjugated

ARP46122_P050-HRP Conjugated

ARP46122_P050-Biotin Conjugated

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Tested Species Reactivity:
Human
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality:
Polyclonal
Host:
Rabbit
Application:
CHIP, WB
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human HIST1H1C
Purification:
Affinity Purified
Predicted Homology Based on Immunogen Sequence:
Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 85%; Rat: 86%
Complete computational species homology data:
Anti-HIST1H1C (ARP46122_P050)
Peptide Sequence:
Synthetic peptide located within the following region: ASGSFKLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKS
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide:
For anti-HIST1H1C (ARP46122_P050) antibody is Catalog # AAP46122 (Previous Catalog # AAPP26984)
Datasheets/Manuals:
Printable datasheet for anti-HIST1H1C (ARP46122_P050) antibody
Sample Type Confirmation:

HIST1H1C is supported by BioGPS gene expression data to be expressed in 721_B

Target Reference:
Kim,K., (2008) J. Biol. Chem. 283 (14), 9113-9126
Gene Symbol:
HIST1H1C
Official Gene Full Name:
Histone cluster 1, H1c
Alias Symbols:
H1.2, H1F2, MGC3992, H1C
NCBI Gene Id:
3006
Protein Name:
Histone H1.2
Description of Target:
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot Id:
P16403
Protein Accession #:
NP_005310
Nucleotide Accession #:
NM_005319
Protein Size (# AA):
213
Molecular Weight:
21kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HIST1H1C.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HIST1H1C.
Protein Interactions:
UBC; CEP250; ATRX; HIST1H3A; LEO1; PAF1; CUL4A; POLR2A; MDM2; ASB16; ASB9; SUZ12; EED; RNF2; APEH; SEC24D; TBCD; PARK2; VHL; UBD; ICAM1; CD81; IGSF8; EIF2AK2; ITGA4; IL7R; CSNK2A2; SMURF1; HIST1H2AD; H1FX; COPS5; CAND1; CUL1; CUL2; CUL3; CUL4B; CUL5; NEDD

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