HINT1 Protein (OPPA02063)

Catalog No: OPPA02063 (Formerly GWB-4FC7CF)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: The HINT1 solution contains 20mM Tris pH-8 & 10% glycerol. Physical appearance: Sterile Filtered colorless solution.
• Host: E. Coli
  Product Introduction: HINT1, also known as Histidine triad nucleotide-binding protein 1 is part of the superfamily named for a near C-terminal HXHXHXX motif (H:Histidine, X:a hydrophobic amino acid) positioned at the *-phosphate of nucleotide substrates. HINT1 hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2. Though it was initially considered to be a protein kinase C inhibitor and act as a haplod-insufficient tumor suppressor including spontaneous tumor formation in Hint+/- and Hint-/-, its actual physiologic function is not known.
  Product Description: HINT1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 126 amino acids (1-126 a.a.) and having a molecular mass of 13.8 kDa.The HINT1 is purified by proprietary chromatographic techniques.
• Reconstitution and Storage: HINT1 although stable 4C for 4 weeks, should be stored desiccated below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
• Purity: Greater than 90.0% as determined by SDS-PAGE.
• Peptide Sequence: MADEIAKAQV ARPGGDTIFG KIIRKEIPAK IIFEDDRCLA FHDISPQAPT HFLVIPKKHI SQISVAEDDD ESLLGHLMIV GKKCAADLGL NKGYRMVVNE GSDGGQSVYH VHLHVLGGRQ MHWPPG.

Target Info

• Gene Symbol: HINT1
• Alias Symbols: HINT, NMAN, PKCI-1, PRKCNH1
• NCBI Gene Id: 3094
• Protein Name: Histidine triad nucleotide-binding protein 1
• Description of Target: Recombinant Human Histidine Triad Nucleotide Binding Protein 1
• Uniprot ID: P49773
• Protein Accession #: NP_005331.1
• Protein Size (# AA): Recombinant