GSTT1 Antibody - N-terminal region (OAAB18136)

Catalog No: OAAB18136

Size:400ul

Western blot analysis of lysates from human brain, rat liver and lung tissue lysate (from left to right), using GSTT1 Antibody (N-term) (Cat. #OAAB18136).
OAAB18136 was diluted at 1:1000 at each lane.
A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody.
Lysates at 35ug per lane.
Dilution: 1:1000

Product Info

• Predicted Species Reactivity: Human, Rat
• Product Format: Liquid. PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB
• Additional Information: Cellular Location: Cytoplasm.
  Tissue Location: Found in erythrocyte. Expressed at low levels in liver. In lung, expressed at low levels in Clara cells and ciliated cells at the alveolar/bronchiolar junction. Absent from epithelial cells of larger bronchioles
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This GSTT1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 46-79 amino acids from the N-terminal region of human GSTT1.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Intended Use: GSTT1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
• Application Info: WB: 1:1000
• Reference: Pemble S., et al.Biochem. J. 300:271-276(1994).
  Jemth P., et al.Arch. Biochem. Biophys. 348:247-254(1997).
  Sprenger R., et al.Pharmacogenetics 10:557-565(2000).
  Iida A., et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
  Kalnine N., et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.

Target Info

• Gene Symbol: GSTT1
• Alias Symbols: Glutathione S-transferase theta-1, GST class-theta-1, Glutathione transferase T1-1, GSTT1
• NCBI Gene Id: 2952
• Description of Target: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1, 2- epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4- nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide.
• Uniprot ID: P30711
• Molecular Weight: 27 kDa