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GSC antibody - N-terminal region (ARP32174_P050)

100 ul
$319.00
In Stock
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Conjugation Options

ARP32174_P050-FITC Conjugated

ARP32174_P050-HRP Conjugated

ARP32174_P050-Biotin Conjugated

Gene Symbol:
GSC
NCBI Gene Id:
145258
Official Gene Full Name:
Goosecoid homeobox
Protein Name:
Homeobox protein goosecoid
Swissprot Id:
P56915
Protein Accession #:
NP_776248
Nucleotide Accession #:
NM_173849
Alias Symbols:
-
Replacement Item:
This antibody may replace item sc-22234 from Santa Cruz Biotechnology.
Description of Target:
GSC regulates chordin (CHRD). GSC may play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis.This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis.
Protein Size (# AA):
257
Molecular Weight:
28kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express GSC.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express GSC.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human GSC
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 86%; Dog: 92%; Human: 100%; Mouse: 85%; Pig: 100%; Rat: 85%
Complete computational species homology data:
Anti-GSC (ARP32174_P050)
Peptide Sequence:
Synthetic peptide located within the following region: FPALHGDSLYGASGGASSDYGAFYPRPVAPGGAGLPAAVSGSRLGYNNYF
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
SMAD3; SMAD1; SMAD2; FOXA2;
Blocking Peptide:
For anti-GSC (ARP32174_P050) antibody is Catalog # AAP32174 (Previous Catalog # AAPP03147)
Datasheets/Manuals:
Printable datasheet for anti-GSC (ARP32174_P050) antibody
Target Reference:
Kohler,A., (2008) Am. J. Med. Genet. A 146 (1), 117-123
Publications:

Behl, M; Hsieh, JH; Shafer, TJ; Mundy, WR; Rice, JR; Boyd, WA; Freedman, JH; Hunter, ES; Jarema, KA; Padilla, S; Tice, RR; Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity. 52, 181-93 (2015). IHC, WB, Cow, Dog, Human, Mouse, Pig, Rat 26386178

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