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Catalog No: OPCD03703
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OPCD03703
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Datasheets/ManualsPrintable datasheet for GRPR Recombinant Protein (OPCD03703)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Residues: Met1-Lys114
Isoelectric Point: 6.5
Subcellular Location: Membrane
Reconstitution and Storage2°C to 8°C|-80°C
Concentration50 ug/mL (prior to lyoph)
Purity> 97%
SourceE.coli
TagN-terminal His Tag
Gene SymbolGRPR
Gene Full Namegastrin releasing peptide receptor
Alias SymbolsBB2;BB2R;bombesin receptor 2;BRS2;gastrin-releasing peptide receptor;GRP-preferring bombesin receptor;GRP-R.
NCBI Gene Id2925
Protein NameGastrin-releasing peptide receptor
Description of TargetReceptor for gastrin-releasing peptide (GRP) (PubMed:1655761). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory (By similarity).
Uniprot IDP30550
Protein Accession #NP_005305.1
Nucleotide Accession #NM_005314.2
Protein Size (# AA)Met1~Lys114
Molecular Weight16kDa
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