GRPR Recombinant Protein (OPCD00913)

Catalog No: OPCD00913

GRPR Recombinant Protein (OPCD00913) using SDS-PAGE

GRPR Recombinant Protein (OPCD00913) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-Leu116
  Subcellular Location: Membrane
  Predicted Isoelectric Point: 7.6
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His and GST Tag

Target Info

• Gene Symbol: Grpr
• Gene Full Name: gastrin releasing peptide receptor
• Alias Symbols: gastrin-releasing peptide receptor;GR;GRP-preferring bombesin receptor;GRP-R.
• NCBI Gene Id: 14829
• Protein Name: Gastrin-releasing peptide receptor
• Description of Target: Receptor for gastrin-releasing peptide (GRP) (PubMed:1671171, PubMed:1707129, PubMed:9345264, PubMed:12526815, PubMed:26658875). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation (PubMed:26658875). Contributes to the regulation of food intake (PubMed:12176666). Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain (PubMed:28280205, PubMed:17653196, PubMed:26658875). Contributes primarily to nonhistaminergic itch sensation (PubMed:28280205). Contributes to long-term fear memory, but not normal spatial memory (PubMed:12526815).
• Uniprot ID: P21729
• Protein Accession #: NP_032203.1
• Nucleotide Accession #: NM_008177.3
• Protein Size (# AA): Met1~Leu116
• Molecular Weight: 43kDa