GRIK2 Recombinant Protein (OPCD00881)

Catalog No: OPCD00881

GRIK2 Recombinant Protein (OPCD00881) using SDS-PAGE

GRIK2 Recombinant Protein (OPCD00881) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Asn286-Pro561
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: GRIK2
• Gene Full Name: glutamate ionotropic receptor kainate type subunit 2
• Alias Symbols: bA487F5.1;EAA4;excitatory amino acid receptor 4;GLR6;GluK2;GluK2(alt_5'UTR);GLUK6;gluR-6;GLUR6;glutamate receptor 6;glutamate receptor form A;glutamate receptor form B;glutamate receptor form C;glutamate receptor form D;glutamate receptor form E;glutamate receptor ionotropic, kainate 2;MRT6;putative NMDtranscript(cassette_171nt).
• NCBI Gene Id: 2898
• Protein Name: Glutamate receptor ionotropic, kainate 2
• Description of Target: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (PubMed:28180184). May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2 (By similarity).
• Uniprot ID: Q13002
• Protein Accession #: NP_001159719.1
• Nucleotide Accession #: NM_001166247.1
• Protein Size (# AA): Asn286~Pro561
• Molecular Weight: 32kDa