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Goat Anti-ADAM17 / TACE Antibody (OAEB01134)

100 ug
$349.00
In Stock
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Gene Symbol:
ADAM17
NCBI Gene Id:
6868
Protein Name:
Disintegrin and metalloproteinase domain-containing protein 17
Swissprot Id:
P78536
Protein Accession #:
NP_003174.3
Alias Symbols:
ADAM17, TACE, a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), CSVP, cSVP, CD156b, CD156b, MGC71942, TACE, cSVPADAM metallopeptidase domain 17, TNF-alpha converting enzyme, a disintegrin and metal
Replacement Item:
This antibody may replace item sc-13973 from Santa Cruz Biotechnology.
Host:
Goat
Clonality:
Polyclonal
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ADAM17.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ADAM17.
Immunogen:
This antibody is expected to recognise isoform 1 (represented by NP_003174) and not isoform 2 (represented by NP_068604).
Predicted Species Reactivity:
Cow, Guinea Pig, Horse, Human, Mouse, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rat: 92%
Complete computational species homology data:
ADAM17 Antibody (OAEB01134)
Peptide Sequence:
LQRQNRVDSKETEC
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Datasheets/Manuals:
Printable datasheet for anti-ADAM17 antibody - OAEB01134
Purity:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application Info:
Peptide ELISA: antibody detection limit dilution 1:128000.
Western Blot: Approx 100kDa band observed in human testis lysates (calculated MW of 93.0kDa according to NP_003174.3). Recommended concentration: 0.1-0.3ug/ml.
Target Reference:
* Black RA, Rauch CT, Kozlosky CJ, Peschon JJ, Slack JL, Wolfson MF, Castner BJ, Stocking KL, Reddy P, Srinivasan S, Nelson N, Boiani N, Schooley KA, Gerhart M, Davis R, Fitzner JN, Johnson RS, Paxton RJ, March CJ, Cerretti DP; A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells.; Nature. 1997 Feb 20;385(6618):729-33; Pubmed 9034190

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