FTH1 Antibody - N-terminal region (ARP54619_P050)

Catalog No: ARP54619_P050

WB Suggested Anti-FTH1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HCT15 cell lysateFTH1 is supported by BioGPS gene expression data to be expressed in HCT15

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Sheep
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FTH1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%
• Peptide Sequence: Synthetic peptide located within the following region: MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALK
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-FTH1 (ARP54619_P050) antibody is Catalog # AAP54619 (Previous Catalog # AAPP31410)
• Sample Type Confirmation:

  FTH1 is supported by BioGPS gene expression data to be expressed in HCT15

Target Info

• Gene Symbol: FTH1
• Gene Full Name: Ferritin, heavy polypeptide 1
• Alias Symbols: FHC, FTH, HFE5, PLIF, FTHL6, PIG15
• NCBI Gene Id: 2495
• Protein Name: Ferritin heavy chain
• Description of Target: FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases.
• Uniprot ID: P02794
• Protein Accession #: NP_002023
• Nucleotide Accession #: NM_002032
• Protein Size (# AA): 183
• Molecular Weight: 21kDa
• Protein Interactions: SDCBP; FTL; FTH1; WDYHV1; CEP57; AURKB; TP53; AURKA; ASB15; ASB16; SUPT16H; SET; MAPK9; MAX; IGSF8; TICAM2; HCVgp1; PIAS4; CDC16; YWHAE; SOX5; MYL3; LBP; KPNA2; GRB2; DAXX; CSNK2B; CDC25A; ATP6V1B1; CD99; SPP1; TRAF4; SUMO2; UBC; Cep55; Trim28; NR1I3; NR3