FEZ1 Antibody (OAPB00543)

Catalog No: OAPB00543

Size:100UG

Western blot analysis of FEZ1 in SK-N-SH cell lysate with FEZ1 antibody at 1 ug/mL in the (A) presence and (B) absence of blocking peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. FEZ1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: FEZ1 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: FEZ1 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FEZ1. The immunogen is located within amino acids 270 - 320 of FEZ1.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-FEZ1 antibody is Catalog # OEPB02662
• Application Info: FEZ1 antibody can be used for the detection of FEZ1 by Western blot at 1 ug/ml. (Optimal dilution should be determined by user)
• Reference: Kuroda S, Nakagawa N, Tokunaga C, et al. Mammalian homologue of the Caenorhabditis elegans UNC-76 protein involved in axonal outgrowth is a protein kinase C z-interacting protein. J. Cell Biol.1999; 144:403-11.;Bloom L and Horvitz HR. The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation. Proc. Natl. Acad. Sci. USA1997; 88:9578-82.; Miyohi K, Honda A, Baba K, et al. Disrupted-in-schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth. Mol. Psychiatry2003; 8:685-94.;Blasius TL, Cai D, Jih GT, et al. Two binding partners cooperate to activate the molecular motor kinesin-1. J. Cell Biol.2007; 176:11-7.

Target Info

• Gene Symbol: FEZ1
• Gene Full Name: fasciculation and elongation protein zeta 1
• Alias Symbols: fasciculation and elongation protein zeta-1;UNC-76;zygin I;zygin-1.
• NCBI Gene Id: 9638
• Protein Name: Fasciculation and elongation protein zeta-1
• Description of Target: May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules.
• Uniprot ID: Q99689
• Molecular Weight: Predicted: 42 kDa Observed: 46 kDa