- Gene Symbol:
- FBXO7
- NCBI Gene Id:
- 25793
- Official Gene Full Name:
- F-box protein 7
- Protein Name:
- F-box only protein 7
- Swissprot Id:
- Q9Y3I1
- Protein Accession #:
- NP_036311
- Nucleotide Accession #:
- NM_012179
- Alias Symbols:
- DKFZp686B08113, FBX, FBX07, FBX7, PKPS, PARK15
- Replacement Item:
- This antibody may replace item sc-271763 from Santa Cruz Biotechnology.
- Description of Target:
- FBXO7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO7 belongs to the Fbxs class and it may play a role in regulation of hematopoiesis.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.
- Protein Size (# AA):
- 522
- Molecular Weight:
- 58kDa
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Purification:
- Affinity Purified
- Application:
- IP, WB
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express FBXO7.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express FBXO7.
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human FBXO7
- Tested Species Reactivity:
- Human
- Predicted Homology Based on Immunogen Sequence:
- Cow: 100%; Dog: 100%; Guinea Pig: 83%; Horse: 92%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 100%; Rat: 93%; Zebrafish: 83%
- Complete computational species homology data:
- Anti-FBXO7 (ARP43128_P050)
- Peptide Sequence:
- Synthetic peptide located within the following region: PGETPSQFPPLRPRFDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDG
- Product Format:
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Reconstitution and Storage:
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
- Concentration:
- Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
- Protein Interactions:
- PSME3; PSMF1; PSMA3; SKP1; TRAF2; MAGED1; SHFM1; PINK1; PARK2; SEC24C; NEDD8; UBC; COPS5; COPS6; CUL1; BIRC2; RBBP6; XPO1; DLGAP5; ELF4; BIRC3; CDK6; UBE2D2; CDC34;
- Blocking Peptide:
- For anti-FBXO7 (ARP43128_P050) antibody is Catalog # AAP43128 (Previous Catalog # AAPP25101)
- Datasheets/Manuals:
- Printable datasheet for anti-FBXO7 (ARP43128_P050) antibody
- Sample Type Confirmation:
FBXO7 is supported by BioGPS gene expression data to be expressed in MCF7
- Target Reference:
- Chang,Y.F., (2006) Biochem. Biophys. Res. Commun. 342 (4), 1022-1026
Product Reviews
- Protocol:
- Tips Information:
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