EXT1 Recombinant Protein (OPCD02988)

Catalog No: OPCD02988

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Cys334-Arg549
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: EXT1
• Gene Full Name: exostosin glycosyltransferase 1
• Alias Symbols: exostoses (multiple) 1;exostosin-1;EXT;Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase;glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase;Langer-Giedion syndrome chromosome region;LGCR;LGS;multiple exostoses protein 1;N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase;putative tumor suppressor protein EXT1;TRPS2;TTV.
• NCBI Gene Id: 2131
• Protein Name: Exostosin-1
• Description of Target: Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).
• Uniprot ID: Q16394
• Protein Accession #: NP_000118.2
• Nucleotide Accession #: NM_000127.2
• Protein Size (# AA): Cys334~Arg549
• Molecular Weight: 27kDa