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- $55: Antibody & Protein in US
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| Datasheets/Manuals | Printable datasheet for ESRRA Antibody (OACA07143) (OACA07143) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Immunohistochemistry |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | Recombinant Human Steroid hormone receptor ERR1 protein (1-423AA) |
| Purification | Affinity Purified |
| Preservative | 0.02% sodium azide |
| Formulation | PBS with, 50% glycerol, pH7.3. |
| Reference | [1]"Communication between the ERRalpha homodimer interface and the PGC-1alpha binding surface via the helix 8-9 loop."Greschik H., Althage M., Flaig R., Sato Y., Chavant V., Peluso-Iltis C., Choulier L., Cronet P., Rochel N., Schuele R., Stroemstedt P.E., Moras D. J. Biol. Chem. 283:20220-20230(2008). [2]"Evidence for ligand-independent transcriptional activation of the human estrogen-related receptor alpha (ERRalpha): crystal structure of ERRalpha ligand binding domain in complex with peroxisome proliferator-activated receptor coactivator-1alpha." Kallen J., Schlaeppi J.-M., Bitsch F., Filipuzzi I., Schilb A., Riou V., Graham A., Strauss A., Geiser M., Fournier B.J. Biol. Chem. 279:49330-49337(2004). [3]"Peroxisome proliferator-activated receptor gamma coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells."Cho Y., Hazen B.C., Russell A.P., Kralli A.J. Biol. Chem. 288:25207-25218(2013). |
| Gene Symbol | ESRRA |
|---|---|
| Gene Full Name | estrogen related receptor alpha |
| Alias Symbols | ERR1;ERRa;ERRalpha;ERR-alpha;ESRL1;estrogen receptor-like 1;estrogen-related nuclear receptor alpha;Estrogen-related receptor alpha;NR3B1;nuclear receptor subfamily 3 group B member 1;steroid hormone receptor ERR1. |
| NCBI Gene Id | 2101 |
| Protein Name | Steroid hormone receptor ERR1 |
| Description of Target | Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle. |
| Uniprot ID | P11474 |
| Protein Accession # | NP_001269379 |
| Nucleotide Accession # | NM_001282450 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ESRRA Antibody (OACA07143)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "ESRRA Antibody (OACA07143)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "ESRRA Antibody (OACA07143)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ESRRA Antibody (OACA07143)"?
This target may also be called "ERR1;ERRa;ERRalpha;ERR-alpha;ESRL1;estrogen receptor-like 1;estrogen-related nuclear receptor alpha;Estrogen-related receptor alpha;NR3B1;nuclear receptor subfamily 3 group B member 1;steroid hormone receptor ERR1." in publications.
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What is the shipping cost for "ESRRA Antibody (OACA07143)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ESRRA Antibody (OACA07143)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ESRRA Antibody (OACA07143)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ESRRA Antibody (OACA07143)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ESRRA"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ESRRA"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ESRRA"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ESRRA"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ESRRA"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ESRRA"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
