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ESR1 Antibody (OACA02432)

100 ug
$315.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
IHC, CHIP
Reconstitution and Storage:
Store at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Replacement Item:
This antibody may replace item sc-102391 from Santa Cruz Biotechnology.
Immunogen:
Recombinant human Estrogen receptor protein
Purification:
Caprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen Sequence:
Human
Datasheets/Manuals:
Printable datasheet for anti-ESR1 (OACA02432) antibody
Specificity:
Human
Formulation:
Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Gene Symbol:
ESR1
Official Gene Full Name:
estrogen receptor 1
Alias Symbols:
ER, ESR, Era, ESRA, ESTRR, NR3A1
NCBI Gene Id:
2099
Protein Name:
estrogen receptor
Description of Target:
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.
Swissprot Id:
P03372
Protein Accession #:
NP_000116.2
Nucleotide Accession #:
NM_000125.3
Protein Size (# AA):
595
Molecular Weight:
66 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ESR1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ESR1.

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