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Catalog No: OACA06858
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OACA06858
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Datasheets/ManualsPrintable datasheet for EIF4A1 Antibody (OACA06858) (OACA06858)
Product Info
Predicted Species ReactivityHuman|Rat
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Reconstitution and Storage-20°C or -80°C
ImmunogenRecombinant Human Eukaryotic initiation factor 4A-I protein (167-406AA)
PurificationAffinity Purified
Preservative0.02% sodium azide
FormulationPBS with, 50% glycerol, pH7.3.
Reference[1]"Comparative structural analysis of human DEAD-box RNA helicases." Schutz P., Karlberg T., van den Berg S., Collins R., Lehtio L., Hogbom M., Holmberg-Schiavone L., Tempel W., Park H.W., Hammarstrom M., Moche M., Thorsell A.G., Schuler H. PLoS ONE 5:E12791-E12791(2010). [2]"Crystal structure of the eIF4A-PDCD4 complex."Chang J.H., Cho Y.H., Sohn S.Y., Choi J.M., Kim A., Kim Y.C., Jang S.K., Cho Y.Proc. Natl. Acad. Sci. U.S.A. 106:3148-3153(2009). [3]"Structural basis for translational inhibition by the tumour suppressor Pdcd4." Loh P.G., Yang H.S., Walsh M.A., Wang Q., Wang X., Cheng Z., Liu D., Song H. EMBO J. 28:274-285(2009).
Gene SymbolEIF4A1
Gene Full Nameeukaryotic translation initiation factor 4A1
Alias SymbolsATP-dependent RNA helicase eIF4A-1;DDX2A;EIF4A;EIF-4A;eIF4A-I;eIF-4A-I;eukaryotic initiation factor 4AI;eukaryotic initiation factor 4A-I;eukaryotic translation initiation factor 4A.
NCBI Gene Id1973
Protein NameEukaryotic initiation factor 4A-I
Description of TargetATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Uniprot IDP60842
Protein Accession #NP_001191439
Nucleotide Accession #NM_001204510
  1. What is the species homology for "EIF4A1 Antibody (OACA06858)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Rat".

  2. How long will it take to receive "EIF4A1 Antibody (OACA06858)"?

    This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".

  3. What buffer format is "EIF4A1 Antibody (OACA06858)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "EIF4A1 Antibody (OACA06858)"?

    This target may also be called "ATP-dependent RNA helicase eIF4A-1;DDX2A;EIF4A;EIF-4A;eIF4A-I;eIF-4A-I;eukaryotic initiation factor 4AI;eukaryotic initiation factor 4A-I;eukaryotic translation initiation factor 4A." in publications.

  5. What is the shipping cost for "EIF4A1 Antibody (OACA06858)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "EIF4A1 Antibody (OACA06858)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "EIF4A1 Antibody (OACA06858)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "EIF4A1 Antibody (OACA06858)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "EIF4A1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "EIF4A1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "EIF4A1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "EIF4A1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "EIF4A1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "EIF4A1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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