- Gene Symbol:
- EED
- NCBI Gene Id:
- 8726
- Official Gene Full Name:
- Embryonic ectoderm development
- Protein Name:
- Polycomb protein EED
- Swissprot Id:
- O75530
- Protein Accession #:
- NP_003788
- Nucleotide Accession #:
- NM_003797
- Alias Symbols:
- HEED, WAIT1
- Replacement Item:
- This antibody may replace item sc-133537 from Santa Cruz Biotechnology.
- Description of Target:
- EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhance
- Protein Size (# AA):
- 441
- Molecular Weight:
- 50kDa
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Purification:
- Affinity Purified
- Application:
- IF, WB
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express EED.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express EED.
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human EED
- Tested Species Reactivity:
- Human, Rat
- Predicted Homology Based on Immunogen Sequence:
- Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 85%
- Complete computational species homology data:
- Anti-EED (ARP35697_P050)
- Peptide Sequence:
- Synthetic peptide located within the following region: GDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSKKCKYSFKC
- Product Format:
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Reconstitution and Storage:
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
- Concentration:
- Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
- Protein Interactions:
- PINK1; BRCA1; ADAM17; EZH2; IMP3; PSPC1; NAT10; PBRM1; RIF1; RBM28; HEATR1; MAGOHB; ARGLU1; MRPL20; NRDE2; CASZ1; BCOR; EXOSC4; LUC7L3; SF3B6; NOP58; SRRT; RAB14; C9orf114; CRNKL1; DDX47; HP1BP3; MYEF2; TRA2A; CPSF1; IGHV3-23; UTP20; PRPF19; ZNF638; RBMX;
- Blocking Peptide:
- For anti-EED (ARP35697_P050) antibody is Catalog # AAP35697 (Previous Catalog # AAPP06943)
- Datasheets/Manuals:
- Printable datasheet for anti-EED (ARP35697_P050) antibody
- Sample Type Confirmation:
EED is strongly supported by BioGPS gene expression data to be expressed in OVCAR3
- Target Reference:
- Rakotobe,D., (er) Virol. J. 5, 32 (2008)
- Publications:
Lin, PC; Huang, HD; Chang, CC; Chang, YS; Yen, JC; Lee, CC; Chang, WH; Liu, TC; Chang, JG; Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2. 16, 583 (2016). IF, WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish 27485439
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