DOK5 Antibody - N-terminal region (OAAB17207)

Catalog No: OAAB17207

Size:400ul

Western blot analysis of anti-DOK5 Pab (Cat. # OAAB17207) in mouse liver tissue lysate. DOK5(arrow) was detected using the purified Pab

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC
• Additional Information: Precautions: DOK5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation
  Tissue Location: Highest expression in skeletal muscle, lower in brain, heart and kidney. Also detected in activated peripheral blood T-lymphocytes
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This DOK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human DOK5.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IHC-P: 1:50~100

Target Info

• Gene Symbol: DOK5
• Alias Symbols: IRS6, IRS-6, C20orf180
• NCBI Gene Id: 55816
• Protein Name: Docking protein 5
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q9P104
• Protein Accession #: NP_060901.2
• Molecular Weight: 35464 Da