| Product Number |
OAAB17207 |
| Product Page |
www.avivasysbio.com/dok5-antibody-n-terminal-region-oaab17207.html |
| Name |
DOK5 Antibody - N-terminal region (OAAB17207) |
| Molecular Weight |
35464 Da |
| Isotype |
Ig |
| NCBI Gene Id |
55816 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
IRS6, IRS-6, C20orf180 |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB17207 |
| Additional Information |
Precautions: DOK5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation |
| Application Info |
WB: 1:1000
IHC-P: 1:50~100 |
| Immunogen |
This DOK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human DOK5. |
| Additional Information |
Tissue Location: Highest expression in skeletal muscle, lower in brain, heart and kidney. Also detected in activated peripheral blood T-lymphocytes |
| Uniprot ID |
Q9P104 |
| Protein Name |
Docking protein 5 |
| Protein Accession # |
NP_060901.2 |
| Gene Symbol |
DOK5 |
| Predicted Species Reactivity |
Human, Mouse |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Human; Mouse |
| Image 1 | Mouse Liver
 | Western blot analysis of anti-DOK5 Pab (Cat. # OAAB17207) in mouse liver tissue lysate. DOK5(arrow) was detected using the purified Pab |
| | Image 2 | breast carcinoma
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
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